Celiac disease cure: I just open the door but you must walk through it yourself

Abstract

Introduction: Celiac disease (CD) is an autoimmune condition characterized by a specific serological and histological profile triggered by gluten ingestion in genetically predisposed individuals. Celiac disease (CD) is the most common autoimmune gastrointestinal disease, affecting nearly 1% of the world population. There are currently no US Food and Drug Administration (FDA)–approved treatments, other than a gluten-free diet (GFD). Chemokines have been widely related to autoimmunity and inflammation, due to their key role in the selective recruitment of leukocytes. CX3CL1 can be found as a membrane-attached protein acting as an adhesion molecule, or as a soluble protein with chemotactic properties.