Rare case of testicular metastasis as a clinical manifestation of pancreatic adenocarcinoma

Abstract

Clinical presentation of underling pancreatic adenocarcinoma (PA) manifested as a testicular metastasis is extremely rare pathology. Our case report is about 46 years old patient with discomfort and chronic pain in the right testicle. Slight swelling, no redness of the skin, no fever. Pain in the epigastrium, loss of appetite, weight loss, nausea and vomiting. Right radical inguinal orchiectomy was performed. Pathohistological and immunohistochemical examination of the specimen revealed adenocarcinoma in rete testis with lymph vascular invasion in ductus deference. Imaging investigation revealed advanced tumor in the distal part of the pancreas. Metastatic tumors in the testis and epididymis represent a clinical manifestation of widespread dissemination of an advanced underlying malignancy, most commonly from the digestive system and usually with poor therapeutic and prognostic outcome.